K
d
values of some Local Anesthetics in kKv 1.5 cardiac potassium channels
(highest values reveal less "cardiotoxicity")
Local Anesthetic
Racemic
S(-)
R(+)
Bupivacaine
8
m
M
27
m
M
4.1
m
M
Ropivacaine
-
81
m
M
32
m
M
IQB-9302
21
m
M
65
m
M
19
m
M